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1,4-Butanediol Diglycidyl Ether - Welinkschem Manufacturer : 1,4-Butanediol diglycidyl ether (BDDE) is a viscous liquid , which is hygroscopic in nature. 1,4-Butanediol Diglycidyl Ether Introduction: 1,4-Butanediol  diglycidyl ether synonym(s): 1,4-Bis (2,3-epoxypropyloxy) butane Empirical Formula (Hill Notation): C10H18O4 CAS Number: 2425-79-8 Molecular Weight: 202.25 Beilstein: 115238 EC Number: 219-371-7 MDL number: MFCD00005146 PubChem Substance ID: 24853198 Properties: vapor pressure ~10 mmHg ( 20 °C) Quality Level: 200 Assay: ≥95% Form: liquid Refractive Index: n20/D 1.453 (lit.) bp:266 °C (lit.) Density: 1.1 g/mL at 25 °C (lit.) 1,4-Butanediol diglycidyl ether (BDDE) is a viscous liquid , which is hygroscopic in nature. BDDE is the most commonly used homobifunctional epoxide compound. BDDE may react with amines, hydroxyls, sulfhydryl groups to produce secondary amines, ether or thioether bonds respectively. Application: BDDE is a cross linking agent used for preparing amylose, x

Long-term toxicity and carcinogenicity studies with 2,4/2,6-toluene-diisocyanate in rats and mice Groups of male and female rats and mice were exposed to 0.05 and 0.15 ppm of  2.6-toluene-diisocyanate  ( TDI ) by inhalation for 6 h/day, 5 days/week for approx. 2 years. Type and incidence of tumours and the number of tumour-bearing animals of either species did not indicate any carcinogenic effect. Haematology, biochemistry, urinalysis, and cytogenicity did not reveal any untoward effect. Increased mortality (females only), reduced weight gain and signs of irritation in the upper and lower respiratory tract resulted from exposure to TDI in the mouse study with the highest incidence in the 0.15 ppm exposure level. Male and female rats of the 0.15 ppm group gained less weight-during the first 12 weeks of the study. Histopathological examination in the rat study has not been completed, but no effect in the respiratory tract or in any other tissue has yet been seen.