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  Tetrahydrofuran (THF) is a colorless, volatile liquid with an ethereal or acetonelike smell and is miscible in water and most organic solvents. E-mail: sales@welinkschem.com Tel / Whatsapp: +86-13548175200 Web: https://www.welinkschem.com

  Why does 1,4 butanediol Produce Hydroxybutyric Acid: 1,4-Butanediol (1,4-BD), a gamma-hydroxybutyrate (GHB) analog with a similarly narrow therapeutic window, is becoming a more common cause of recreational overdose. After oral administration, 1,4-butanediol will generate hydroxybutyric acid (GHB) through the reaction catalyzed by lactonase, alcohol dehydrogenase and acetaldehyde dehydrogenase. Hydroxybutyric acid is a central nervous system depressant, which can inhibit dopamine nerve cells in the human body, thereby increasing the concentration of dopamine at the nerve endings and causing an excitatory response. This is why 1.4 butanediol produces hydroxybutyrate. .1,4-butanediol  (BDO) can produce hydroxybutyric acid (GHB) through a series of chemical reactions. Here is a brief explanation of the process: 1. Oxidation: BDO can be oxidized using various methods, such as oxidation with potassium permanganate (KMnO4) or chromium trioxide (CrO3). This oxidation converts one of the alc

  Welinks produces 1,4-butanediol in batches, suitable for small and medium-sized manufacturers. E-mail: sales@welinkschem.com Tel / Whatsapp: +86-13548175200 Web: https://www.welinkschem.com

  How to Prepare GHB from 1,4-butanediol? GHB can be prepared from  1,4-butanediol  through the following steps: Step 1: Preparation of γ-butyrolactone 1,4-butanediol and phenylacetic acid are heated and reacted with a certain catalyst to generate γ-butyrolactone. This step is a key step in preparing GHB. Step 2: Hydrolysis Reaction Dissolve the γ-butyrolactone obtained in step 1 in water, add sodium hydroxide (NaOH) solution, and fully stir. Through the hydrolysis reaction, γ-butyrolactone is converted to GHB. How to Prepare GHB from 1,4-butanediol Step 3: Extraction and Purification The mixed solution obtained from the hydrolysis reaction is subjected to appropriate extraction and purification steps, for example, extraction with an organic solvent, followed by distillation, etc., to obtain GHB with high purity. It is important to note that GHB is a regulated psychotropic substance that is listed as illegal or restricted for use in most countries. Before proceeding with any laboratory

  Welinks is chemical liquid production and transportation company E-mail: sales@welinkschem.com Tel / Whatsapp: +86-13548175200 Web: https://www.welinkschem.com

  What is Tetrahydrofuran? Tetrahydrofuran  is an organic compound with the chemical formula C4H8O. It is a colorless liquid with an ether-like odor at normal temperature and pressure. Tetrahydrofuran is an important solvent, which can be used in organic synthesis, catalytic reaction and extraction and separation of certain organic compounds. It is widely used in solvents, extractants and media in the chemical industry. Tetrahydrofuran has low toxicity and volatility, is relatively stable, and can be used as a substitute in many cases. The structure of tetrahydrofuran can be regarded as a link between an oxygen atom on the furan ring and a hydrogen atom. It has high polarity and can dissolve many organic compounds and some inorganic salts. There are two imine (imine) carbon-nitrogen bonds inside its molecule. The existence of this bond makes THF act as a catalyst in some reduction reactions. What is Tetrahydrofuran In the field of organic synthesis, tetrahydrofuran is often used as a s

  This is the video of Welinks' foreign trade shipment of BDO. 1.4-Butanediol and its derivatives are widely used in the production of plastics, solvents, electronic chemicals and elastic fibers. E-mail: sales@welinkschem.com Tel / Whatsapp: +86-13548175200 Web: https://www.welinkschem.com

  Properties and Applications of Tetrahydrofuran: Tetrahydrofuran  is an organic compound with a chemical formula of C4H8O, which belongs to cyclic ether compounds. The properties and applications of tetrahydrofuran will be introduced below. 1. Nature: Tetrahydrofuran is a colorless and transparent liquid with low volatility at room temperature. It is soluble in water, ethanol, and various organic solvents, and has good compatibility with other organic substances. Tetrahydrofuran has strong chemical properties and is not easily oxidized or hydrolyzed. Properties and Applications of Tetrahydrofuran 2. Application: (1) Solvent: Tetrahydrofuran has excellent solubility and is a widely used solvent. Because it can dissolve both polar substances and non-polar substances, it is widely used in the fields of organic synthesis, chemical analysis and biochemistry. Tetrahydrofuran also has important application value in polymerization reaction, solid phase synthesis, catalyst carrier and so on. (